A two-time Gold Glove victor, Cano began his Major League Baseball career with the Yankees in 2005 and signed as a free agent with Seattle in 2013. Cano tested positive before the season.
If no games are postponed, Cano would be eligible to return August 14 at Oakland.
"For more than 15 years, playing professional baseball has been the greatest honor and privilege of my life", Cano said in part.
Update: Cano says in a statement he tested positive for Furosemide, a substance he claims is not a PED. This was the most hard decision I have ever made in my life, but ultimately the right decision given that I do not dispute that I was given this substance. This was the most hard decision I have ever made in my life, but ultimately the right decision given that I do not dispute that I was given this substance. I apologize to my family, friends, fans, teammates and the Mariners organization.
Furosemide is used to treat heart problems, high blood pressure and is a diuretic, which WebMD states, "causes you to make more urine". Furosemide itself isn't against the league's rules, but if MLB determines a player was using it as a masking agent, the drug triggers a positive test.
After Martin made that determination, the union filed a grievance last month. MLB Senior Vice President Patrick Houlihan and union deputy general counsel Matt Nussbaum then worked to reach the agreement to accept the discipline. In his five years with the Mariners, Cano has been a three-time All-Star with a.294 batting average, 101 home runs and 384 RBI.
The Mariners subsequently released a statement of their own, which read: "Robinson made a mistake". Our organization fully supports the Program.
The suspension comes on the heels of Cano suffering the first significant injury of his tenure in Seattle.
Cano, a staple at second base, was set to miss an extended period anyway after he broke a bone in his hand Sunday, when he got struck by a pitch. Following the injury, Cano was placed on the disabled list and was scheduled to go to Philadelphia to see a specialist.
The 80-game suspension is without pay, meaning Cano will miss out on almost half of the $24 million that he was owed for the 2018 season.
Major League Baseball said the suspension is effective immediately. He will lose his salary for the 80 games, an accumulation of more than $11 million.
Cano is an eight-time MLB All-Star with 305 career home runs and more than 2,400 hits.
This changes the entire complexion of the Mariners' season.