Berger, 24, is the fourth repeat victor at St. Jude and the first since David Toms did it in 2003 and '04.
Two-time U.S. Open champion Retief Goosen and Chez Reavie each shot a 66 on the par-70 TPC Southwind course.
Chasing his sixth TOUR title and first since here in 2014 (76 starts ago), the World No. 461 began T1 with Rafa Cabrera Bello and Stewart Cink.
Ben Crane walks between the second and third holes during the final round of the St. Jude Classic golf tournament Sunday, June 11, 2017, in Memphis, Tenn.
Langer, who has almost made $1.7 million so far this season to lead the tour, won the Regions Tradition by five shots and the recent Senior PGA Championship by a stroke.
Not the U.S. Open - that's next week - but the St. Jude Classic in Memphis.
Internationals Charl Schwartzel and Kim Whee were tied for the runner-up at nine under.
ATZENBRUGG, Austria - Chilean golfer Felipe Aguilar shot a 7-under 65 to build a two-stroke lead over a group of three on a sunny opening day of the Lyoness Open on Thursday.
"I definitely like playing the week before majors", Fowler said. "I just battled so hard today and played so good, I just can't be happier".
Phil Mickelson briefly had a share of the lead but had triple bogey on No. 12, including a shot into the water. Better play from tee to green would give him a chance to make a serious charge.
Jutanugarn shot a 3-under 69 in the final round and was tied with Thompson and Chun at 17-under 271 heading into the playoff. She three-putted from 35 feet on the 18th and missed a 4-footer for the win.
Jodi Ewart Shadoff of England (69) was one shot back in fourth place.
Suzann Pettersen of Norway had a 71 to move to 9 under while fellow first-round co-leader Mi Hyang Lee of South Korea remained at 8 under with a 72.
The 24-year-old's one-shot victory saw him follow in the footsteps of David Toms, who won the trophy in 2003 and 2004, after the American claimed his maiden PGA Tour title at this tournament last year.