Bills vs. Panthers Point Spread: NFL Week 2 Odds, Prediction

It may be a homecoming for McDermott back at Bank of America Stadium, but the Panthers have too much talent to let their first home game of the season turn into their first loss of 2017.

These teams are similar in many ways, starting with their dual threat quarterbacks. Carolina took a 7-0 lead late in the first quarter on a 40-yard Cam Newton-to-Russell Shepard scoring hook-up and eventually pushed that to 23-0 late in the third, before allowing the 49ers to hit the board for the only time with a field goal. "Anything that I see on tape, I can ask him about", Taylor said. Known for his ability to make plays with his legs, Newton can be unsafe if given running room. "Which means the d-line has to stay in their lanes, and as a secondary, you have to be able to cover probably a lot longer than you're used to covering". Jordan Matthews and Zay Jones both have potential, but neither of them have stood out yet.

Last season, Charles Clay led the Bills in receptions with 57.

Buffalo Bills running back LeSean McCoy will miss practice on Friday due to a sore groin, according to head coach Sean McDermott. One of the top rushers in the National Football League through Week 1, McCoy is looking primed for another standout performance.

McDermott spent the last 6 years with the Panthers as the team's defensive coordinator but now is at the helm for the Bills, with a chance to defeat his former team on the road. Kuechly and McCoy will be a highlight matchup this week. And have you heard Buffalo has a few guys that played with the Panthers? "But if they give you a different look, you're not going to force it. I'm just going to do what I have to do for the best [interests] of the team".

"It was a little challenging trying to get the ball rolling and working moves, wanting to get to the QB, trying to flash here, flash here, throw your fastball". The Bills will be hoping his new surroundings will help him return to the form, which saw him register 110 total tackles, 3.5 sacks and two forced fumbles during the 2014 season. They're doing what's best for the whole team. But they're certainly not looking at it that way.

Captains Kyle Williams, Lorenzo Alexander, and crew will have to make big plays, force turnovers, and set the offense up with good field position in order to keep this game close. Treat it like any other game.

Buffalo's defense is still a work in progress, but two-time Pro Bowl defensive tackle Marcell Dareus can hold the point, and a McDermott defense will be all about disciplined gap control. "We've just got to be on top of the things that they do".

Vanessa Coleman