The president Mamnoon Hussain and the chief of staff of the pakistan army, Qamar Javed Bajwa condemned the attack.
Another attack in June injured three security officials after an improvised explosive device targeted their vehicle in the Johan area of Kalat.
Pakistan Army is under constants attacks by terrorists as it is conducting a new operation to flush out terrorists from their hideouts.
Provincial home minister Sarfraz Bugti and government spokesman Anwar ul Haq Kakar confirmed the death toll and put the number of wounded at 32.
The COAS also visited injured of Quetta blast at Combined Military Hospital (CMH) Quetta Cantt.
"The target was a security forces vehicle", said Home Minister Sarfaraz Bugti.
Latest attack on Pakistan Army by terrorists took just two days before Pakistan is going to celebrate its 70th Independence Day.
A military statement said the bomb also wounded 25 people, including 15 civilians.
Investigators and senior security and police officers remained at the site of the terror incident to collect evidence and probe the incident. "Our resolve won't succumb to any challenge", Gen Bajwa was quoted as saying. As a result nearby vehicles caught fire.
The Balochistan Assembly, Quetta Law College, a private hospital and many offices are located in the vicinity where the explosion occurred.
Mineral-rich Balochistan, where Gwader is located, has been plagued for decades by a separatist insurgency and sectarian killings.
Militants of the group islamic State and the taliban have already attacked the city of Quetta in the past.